Toxicology Research Today is a free monthly online journal that collates and summarizes the latest research about Toxicology, including details on forensic toxicology, carcinogenicity, assays. | ||||||||
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Ecotoxicology of ozone: bioactivation of extracellular ascorbate.Sandermann H Ecotox.freiburg, Schubertstr. 1, D-79104 Freiburg, Germany. The ascorbate pools of the extracellular respiratory lining fluids and the plant apoplast are currently considered as part of the first line of defence against ambient ozone. Ozone is in fact rapidly decomposed by ascorbate, but the only product identified so far (singlet oxygen) is toxic. Peroxy-l-threonic and peroxy-oxalic acids are now derived as further decomposition products on the basis of Criegee-type ozone chemistry. These secondary toxicants may resemble known ozone induced transmitter molecules by participating in signalling events affecting plant and animal innate immunity. Published 2 January 2008 in Biochem Biophys Res Commun, 366(2): 271-4.
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