Toxicology Research Today is a free monthly online journal that collates and summarizes the latest research about Toxicology, including details on forensic toxicology, carcinogenicity, assays.

Volume 5 (2009), Issue 12 (December)

1. Correlation of the time course of development and decay of tolerance to morphine with alterations in sodium pump protein isoform abundance.
   Biochem Pharmacol. [Abstract] [Full-text]
2. Ofloxacin induces oxidative damage to joint chondrocytes of juvenile rabbits: excessive production of reactive oxygen species, lipid peroxidation and DNA damage.
   Eur J Pharmacol, 626(2): 146-53. [Abstract] [Full-text]
3. Neuroprotective effect of 5,7,3',4',5'-pentahydroxy dihydroflavanol-3-O-(2''-O-galloyl)-beta-D-glucopyranoside, a polyphenolic compound in focal cerebral ischemia in rat.
   Eur J Pharmacol, 626(2): 205-12. [Abstract] [Full-text]
4. Effects of an onion by-product on bioactivity and safety markers in healthy rats.
   Br J Nutr, 102(11): 1574-82. [Abstract] [Full-text]
5. Flow cytometry peripheral blood micronucleus test in vivo: Determination of potential thresholds for aneuploidy induced by spindle poisons.
   Environ Mol Mutagen. [Abstract] [Full-text]
6. Repeated preexposure or coexposure to arsenic differentially alters acetaminophen-induced oxidative stress in rat kidney.
   Environ Toxicol. [Abstract] [Full-text]
7. Clinical Significance of Ephrin (Eph)-A1, -A2, -A4, -A5 and -A7 Receptors in Pancreatic Ductal Adenocarcinoma.
   Pathol Oncol Res. [Abstract] [Full-text]
8. The role of general practitioners in promoting cervical cancer screening: a field survey in a rural area of Crete, Greece.
   Eur J Cancer Prev. [Abstract] [Full-text]
9. Subchronic phencyclidine in rats: alterations in locomotor activity, maze performance, and GABAA receptor binding.
   Behav Pharmacol. [Abstract] [Full-text]
10. Breakfast consumption among children and adolescents in the Netherlands.
    Eur J Public Health. [Abstract] [Full-text]
11. Mixture optimization of six core glycosyl hydrolases for maximizing saccharification of ammonia fiber expansion (AFEX) pretreated corn stover.
    Bioresour Technol. [Abstract] [Full-text]
12. Effect of metal accumulation on metallothionein level and condition of the periwinkle Littorina littorea along the Scheldt estuary (the Netherlands).
    Environ Pollut. [Abstract] [Full-text]
13. Population genetics of Y-chromosome STRs in a population of Northern Greeks.
    Forensic Sci Int Genet, 4(1): e21-2. [Abstract] [Full-text]
14. Genetic variation of 15 autosomal STR loci in a Somali population.
    Forensic Sci Int Genet, 4(1): e19-20. [Abstract] [Full-text]
15. Improving compound quality through in vitro and in silico physicochemical profiling.
    Chem Biodivers, 6(11): 1760-6. [Abstract] [Full-text]
16. Expression and function of p-glycoprotein in normal tissues: effect on pharmacokinetics.
    Methods Mol Biol, 596: 199-222. [Abstract] [Full-text]
17. Particle size distributions of silver nanoparticles at environmentally relevant conditions.
    J Chromatogr A, 1216(52): 9099-105. [Abstract] [Full-text]
18. Melanoma incidence and exposure to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers.
    Cancer Epidemiol, 33(5): 391-5. [Abstract] [Full-text]
19. Doxorubicin acts through tumor necrosis factor receptor subtype 1 to cause dysfunction of murine skeletal muscle.
    J Appl Physiol, 107(6): 1935-42. [Abstract] [Full-text]
20. A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain.
    Eur J Clin Nutr, 63(12): 1387-93. [Abstract] [Full-text]
21. The canine kallikrein-related peptidases 9 and 10: structural characterization and expression in mammary cancer.
    Mamm Genome. [Abstract] [Full-text]
22. Effect of self-measurement of blood pressure on adherence to treatment in patients with mild-to-moderate hypertension.
    J Hypertens. [Abstract] [Full-text]
23. Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis.
    Sci Signal, 2(99): ra78. [Abstract] [Full-text]
24. Science signaling podcast: 1 december 2009.
    Sci Signal, 2(99): pc22. [Abstract] [Full-text]
25. High DNA Methyltransferase 3B Expression Mediates 5-Aza-Deoxycytidine Hypersensitivity in Testicular Germ Cell Tumors.
    Cancer Res. [Abstract] [Full-text]
26. Chronic Ethanol Consumption Results in Atypical Liver Injury in Copper/Zinc Superoxide Dismutase Deficient Mice.
    Alcohol Clin Exp Res. [Abstract] [Full-text]
27. Calpain activation and Na(+)/Ca(2+) exchanger degradation occur downstream of calcium deregulation in hippocampal neurons exposed to excitotoxic glutamate.
    J Neurosci Res. [Abstract] [Full-text]
28. Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity.
    J Toxicol Environ Health A, 73(1): 58-73. [Abstract] [Full-text]
29. Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma.
    Proc Natl Acad Sci U S A, 106(48): 20312-7. [Abstract] [Full-text]
30. Pycnogenol((R)) improves left ventricular function in streptozotocin-induced diabetic cardiomyopathy in rats.
    Phytother Res. [Abstract] [Full-text]
31. Withanamides in Withania somnifera fruit protect PC-12 cells from beta-amyloid responsible for Alzheimer's disease.
    Phytother Res. [Abstract] [Full-text]
32. An unusual suicidal death by automobile antenna: a case report.
    Diagn Pathol, 4: 40. [Abstract] [Full-text]
33. Human rRNA gene clusters are recombinational hotspots in cancer.
    Cancer Res, 69(23): 9096-104. [Abstract] [Full-text]
34. Liquid chromatography-tandem mass spectrometric assay for the light sensitive tyrosine kinase inhibitor axitinib in human plasma.
    J Chromatogr B Analyt Technol Biomed Life Sci, 877(32): 4090-6. [Abstract] [Full-text]
35. The physiologic effects of caloric restriction are reflected in the in vivo adipocyte-enriched proteome of overweight/obese subjects.
    J Proteome Res, 8(12): 5532-40. [Abstract] [Full-text]
36. Toxicity of hexachloronaphthalene (HxCN) and induction of CYP 1A in rats.
    Ecotoxicol Environ Saf, 73(2): 196-205. [Abstract] [Full-text]
37. The absence of functional dectin-1 on enterocytes may serve to prevent intestinal damage.
    Eur J Gastroenterol Hepatol, 22(1): 88-94. [Abstract] [Full-text]
38. Pathological and Immunohistochemical Examinations of the Pancreas in Subacute Endosulfan Toxicity in Rabbits.
    Pancreas. [Abstract] [Full-text]
39. Utility and relationships of biomarkers of smoking in African-American light smokers.
    Cancer Epidemiol Biomarkers Prev, 18(12): 3426-34. [Abstract] [Full-text]
40. Reconciling human smoking behavior and machine smoking patterns: implications for understanding smoking behavior and the impact on laboratory studies.
    Cancer Epidemiol Biomarkers Prev, 18(12): 3305-20. [Abstract] [Full-text]
41. Evaluation of in vitro assays for assessing the toxicity of cigarette smoke and smokeless tobacco.
    Cancer Epidemiol Biomarkers Prev, 18(12): 3263-304. [Abstract] [Full-text]
42. NanoART synthesis, characterization, uptake, release and toxicology for human monocyte-macrophage drug delivery.
    Nanomed, 4(8): 903-17. [Abstract] [Full-text]
43. 10 years of oral anticoagulant pharmacogenomics: what difference will it make? A critical appraisal.
    Pharmacogenomics, 10(12): 1955-65. [Abstract] [Full-text]
44. Quantitative determination of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8-dihydroguanosine, and their non-oxidized forms: daily concentration profile in healthy volunteers.
    Biomarkers. [Abstract] [Full-text]
45. Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material.
    J Chromatogr B Analyt Technol Biomed Life Sci, 877(32): 4115-24. [Abstract] [Full-text]
46. Protracted exposure to supraphysiological levels of corticosterone does not cause neuronal loss or damage and protects against kainic acid-induced neurotoxicity in the hippocampus of C57BL/6J mice.
    Neurotoxicology, 30(6): 965-76. [Abstract] [Full-text]
47. Benzene-initiated oxidative stress: Effects on embryonic signaling pathways.
    Chem Biol Interact. [Abstract] [Full-text]
48. Evaluation of a modified comet assay to detect DNA damage in mammalian sperm exposed in vitro to different mutagenic compounds.
    Reprod Toxicol. [Abstract] [Full-text]
49. Development of a unit risk factor for 1,3-butadiene based on an updated carcinogenic toxicity assessment.
    Risk Anal, 29(12): 1726-42. [Abstract] [Full-text]
50. Di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate inhibit growth and reduce estradiol levels of antral follicles in vitro.
    Toxicol Appl Pharmacol, 242(2): 224-30. [Abstract] [Full-text]
51. Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation.
    J Biol Chem, 284(50): 35144-53. [Abstract] [Full-text]
52. Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.
    Toxicol Appl Pharmacol, 242(2): 182-90. [Abstract] [Full-text]
53. Down-regulation of c-Cbl by morphine accounts for persistent ERK1/2 signaling in delta-opioid receptor-expressing HEK293 cells.
    J Biol Chem, 284(50): 34819-28. [Abstract] [Full-text]
54. The interaction of reward genes with environmental factors in contribution to alcoholism in mexican americans.
    Alcohol Clin Exp Res, 33(12): 2103-12. [Abstract] [Full-text]
55. Polymorphisms of delta-aminolevulinic acid dehydratase (ALAD) and peptide transporter 2 (PEPT2) genes in children with low-level lead exposure.
    Neurotoxicology, 30(6): 881-7. [Abstract] [Full-text]
56. Detection of acute fentanyl exposure in fresh and decomposed skeletal tissues part II: The effect of dose-death interval.
    Forensic Sci Int. [Abstract] [Full-text]
57. Infected atopic dermatitis lesions contain pharmacologic amounts of lipoteichoic acid.
    J Allergy Clin Immunol. [Abstract] [Full-text]
58. World Health Organization reference values for human semen characteristics.
    Hum Reprod Update. [Abstract] [Full-text]
59. Dephosphorylation of threonine 38 is required for nuclear translocation and activation of human xenobiotic receptor CAR (NR1I3).
    J Biol Chem, 284(50): 34785-92. [Abstract] [Full-text]
60. Melanoma antigen gene protein-A11 (MAGE-11) F-box links the androgen receptor NH2-terminal transactivation domain to p160 coactivators.
    J Biol Chem, 284(50): 34793-808. [Abstract] [Full-text]
61. Immunotoxicity testing in nonhuman primates.
    Methods Mol Biol, 598: 341-59. [Abstract] [Full-text]
62. The delayed type hypersensitivity assay using protein and xenogeneic cell antigens.
    Methods Mol Biol, 598: 185-94. [Abstract] [Full-text]
63. Markers of inflammation.
    Methods Mol Biol, 598: 53-73. [Abstract] [Full-text]
64. Microbial contamination of milk and dairy products from restaurants in Spain.
    Foodborne Pathog Dis, 6(10): 1269-72. [Abstract] [Full-text]
65. Mitochondrial dysfunction in amyotrophic lateral sclerosis.
    Biochim Biophys Acta, 1802(1): 45-51. [Abstract] [Full-text]
66. Acute toxicity of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) in male Sprague-Dawley rats: Effects on hepatic oxidative stress, glutathione and metals status.
    Environ Int. [Abstract] [Full-text]
67. Toxic threshold of dietary microcystin (-LR) for quart medaka.
    Toxicon. [Abstract] [Full-text]
68. Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice.
    J Clin Invest, 119(12): 3597-3612. [Abstract] [Full-text]
69. Cross-neutralisation of Australian brown snake, taipan and death adder venoms by monovalent antibodies.
    Vaccine, 28(3): 798-802. [Abstract] [Full-text]
70. Stress sensitivity is increased in transgenic rats with low brain angiotensinogen.
    J Endocrinol, 204(1): 85-92. [Abstract] [Full-text]
71. Abnormal Neurovascular Control in Anabolic Androgenic Steroids Users.
    Med Sci Sports Exerc. [Abstract] [Full-text]
72. Prothrombin Complex Concentrate Versus Recombinant Factor VIIa for Reversal of Hemodilutional Coagulopathy in a Porcine Trauma Model.
    J Trauma. [Abstract] [Full-text]
73. Pleural effects of indium phosphide in b6c3f1 mice: nonfibrous particulate induced pleural fibrosis.
    Exp Lung Res, 35(10): 858-82. [Abstract] [Full-text]
74. In vitro footprinting of promoter regions within supercoiled plasmid DNA.
    Methods Mol Biol, 613: 223-33. [Abstract] [Full-text]
75. Divergence among an international population of Trichophyton tonsurans isolates.
    Mycopathologia, 169(1): 1-13. [Abstract] [Full-text]
76. Beta-carotene affects oxidative stress-related DNA damage in lung epithelial cells and in ferret lung.
    Carcinogenesis, 30(12): 2070-6. [Abstract] [Full-text]
77. Comet assay in murine bone-marrow cell line (FDC-P2).
    Toxicol In Vitro. [Abstract] [Full-text]
78. Closing the environmental toxicology gap.
    Environ Sci Technol, 43(24): 9050-1. [Abstract] [Full-text]
79. Evaluation of medical countermeasures against organophosphorus compounds: The value of experimental data and computer simulations.
    Chem Biol Interact. [Abstract] [Full-text]
80. Synergistic anti-cancer activity by the combination of TRAIL/APO-2L and celastrol.
    Cancer Invest, 28(1): 23-32. [Abstract] [Full-text]
81. Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1.
    Biochem Pharmacol. [Abstract] [Full-text]
82. Usage pattern and exposure assessment of food colours in different age groups of consumers in the State of Uttar Pradesh, India.
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 27(2): 181-9. [Abstract] [Full-text]
83. Characterization of the oestrogenic activity of non-aromatic steroids: are there male-specific endogenous oestrogen receptor modulators?
    Br J Pharmacol, 158(7): 1796-807. [Abstract] [Full-text]
84. XJW20, a novel oxoindole derivative, induces G2/M arrest and apoptosis selectively in K562 leukemia cell line.
    Chem Biol Interact, 183(1): 133-41. [Abstract] [Full-text]
85. Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure.
    Mutat Res, 683(1): 57-67. [Abstract] [Full-text]
86. The modulatory effects of garlic oil on hepatic cytochrome P450s in mice.
    Hum Exp Toxicol, 28(12): 777-83. [Abstract] [Full-text]
87. Activation of inflammatory response and apoptosis of polymorphonuclear leukocytes in patients with argemone oil poisoning.
    Chem Biol Interact, 183(1): 154-64. [Abstract] [Full-text]
88. Sesamin attenuates behavioral, biochemical and histological alterations induced by reversible middle cerebral artery occlusion in the rats.
    Chem Biol Interact, 183(1): 255-63. [Abstract] [Full-text]
89. Dose-response modeling of high-throughput screening data.
    J Biomol Screen, 14(10): 1216-27. [Abstract] [Full-text]
90. Effects of methiocarb on lipid peroxidation and glutathione level in rat tissues.
    Drug Chem Toxicol, 33(1): 50-4. [Abstract] [Full-text]
91. Vascular endothelial growth factor-C (VEGF-C) promotes angiogenesis by induction of COX-2 in leukemic cells via the VEGF-R3/JNK/AP-1 pathway.
    Carcinogenesis, 30(12): 2005-13. [Abstract] [Full-text]
92. High urinary excretion of lipid peroxidation-derived DNA damage in patients with cancer-prone liver diseases.
    Mutat Res, 683(1): 23-8. [Abstract] [Full-text]
93. Drastic decrease in dopamine receptor levels in the striatum of acetylcholinesterase knock-out mouse.
    Chem Biol Interact, 183(1): 194-201. [Abstract] [Full-text]
94. The divalent metal transporter homologues SMF-1/2 mediate dopamine neuron sensitivity in caenorhabditis elegans models of manganism and parkinson disease.
    J Biol Chem, 284(51): 35758-68. [Abstract] [Full-text]
95. Effects of extended cocaine access and cocaine withdrawal on choice between cocaine and food in rhesus monkeys.
    Neuropsychopharmacology, 35(2): 493-504. [Abstract] [Full-text]
96. A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis.
    Blood, 114(25): 5236-44. [Abstract] [Full-text]
97. Real-time xCELLigence impedance analysis of the cytotoxicity of dental composite components on human gingival fibroblasts.
    Dent Mater, 26(1): 51-8. [Abstract] [Full-text]
98. The mammalian aryl hydrocarbon (Ah) receptor: from mediator of dioxin toxicity toward physiological functions in skin and liver.
    Biol Chem, 390(12): 1225-35. [Abstract] [Full-text]
99. Alteration of the nuclear pore complex in Ca(2+)-mediated cell death.
    Cell Death Differ, 17(1): 119-33. [Abstract] [Full-text]
100. Chronic boron exposure and human semen parameters.
     Reprod Toxicol. [Abstract] [Full-text]
101. Plasma dispositions of ivermectin, doramectin and moxidectin following subcutaneous administration in rabbits.
     Lab Anim. [Abstract] [Full-text]
102. Quantification of cortisol and 6 beta-hydroxycortisol in human urine by LC-MS/MS, and gender-specific evaluation of the metabolic ratio as biomarker of CYP3A activity.
     J Chromatogr B Analyt Technol Biomed Life Sci, 878(1): 97-101. [Abstract] [Full-text]
103. Combining functional magnetic resonance imaging with mouse genomics: new options in pain research.
     Neuroreport, 21(1): 29-33. [Abstract] [Full-text]
104. Genotoxic thresholds, DNA repair, and susceptibility in human populations.
     Toxicology. [Abstract] [Full-text]
105. Importance of membrane-bound catechol-O-methyltransferase in L-DOPA metabolism: a pharmacokinetic study in two types of Comt gene modified mice.
     Br J Pharmacol, 158(8): 1884-94. [Abstract] [Full-text]
106. The role of oxidative stress in Sudan IV-induced DNA damage in human liver-derived HepG2 cells.
     Environ Toxicol. [Abstract] [Full-text]
107. Genetic association between intronic variants in AS3MT and arsenic methylation efficiency is focused on a large linkage disequilibrium cluster in chromosome 10.
     J Appl Toxicol. [Abstract] [Full-text]
108. Sclerocarya birrea (a. rich) hochst. ['marula'] (anacardiaceae): a review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses.
     Phytother Res. [Abstract] [Full-text]
109. Interactions of aluminum nanoparticles with human epidermal keratinocytes.
     J Appl Toxicol. [Abstract] [Full-text]
110. Acute barium toxicity from ingestion of "snake" fireworks.
     J Med Toxicol, 5(4): 209-13. [Abstract] [Full-text]
111. Infants' exposure to aluminum from vaccines and breast milk during the first 6 months.
     J Expo Sci Environ Epidemiol. [Abstract] [Full-text]
112. Lack of Evidence for the Role of Human Adenovirus-36 in Obesity in a European Cohort.
     Obesity (Silver Spring). [Abstract] [Full-text]
113. Proceedings of the 2009 National Toxicology Program Satellite Symposium.
     Toxicol Pathol. [Abstract] [Full-text]
114. Cellular mechanisms of central nervous system repair by natural autoreactive monoclonal antibodies.
     Arch Neurol, 66(12): 1456-9. [Abstract] [Full-text]
115. Highly Cited Articles in Environmental and Occupational Health, 1919-1960.
     Arch Environ Occup Health, 64: 32-42. [Abstract] [Full-text]
116. Improved 3D-QSAR analyzes for the predictive toxicology of polybrominated diphenyl ethers with CoMFA/CoMSIA and DFT.
     Ecotoxicol Environ Saf. [Abstract] [Full-text]
117. Possible effect of gene polymorphisms on the release of TNFalpha and IL1 cytokines in coal workers' pneumoconiosis.
     Exp Toxicol Pathol. [Abstract] [Full-text]
118. Ecological vulnerability in risk assessment - A review and perspectives.
     Sci Total Environ. [Abstract] [Full-text]
119. Methylenetetrahydrofolate reductase polymorphisms, serum methylenetetrahydrofolate reductase levels, and risk of childhood acute lymphoblastic leukemia in a Chinese population.
     Cancer Sci. [Abstract] [Full-text]
120. Adolescent toluene exposure produces enduring social and cognitive deficits in mice: An animal model of solvent-induced psychosis.
     World J Biol Psychiatry. [Abstract] [Full-text]
121. Tissue engineering of lung: the effect of extracellular matrix on the differentiation of embryonic stem cells to pneumocytes.
     Tissue Eng Part A. [Abstract] [Full-text]
122. Modeling the Global Fate and Transport of Perfluorooctane Sulfonate (PFOS) and Precursor Compounds in Relation to Temporal Trends in Wildlife Exposure.
     Environ Sci Technol, 43(24): 9274-80. [Abstract] [Full-text]
123. Spatially Resolved Distribution Models of POP Concentrations in Soil: A Stochastic Approach Using Regression Trees.
     Environ Sci Technol, 43(24): 9230-6. [Abstract] [Full-text]
124. Evaluation of small arms range soils for metal contamination and lead bioavailability.
     Environ Sci Technol, 43(24): 9071-6. [Abstract] [Full-text]
125. Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G.
     Mol Cancer Ther, 8(12): 3331-40. [Abstract] [Full-text]
126. Smoking-Related Gene Expression in Laser Capture-Microdissected Human Lung.
     Clin Cancer Res, 15(24): 7562-7570. [Abstract] [Full-text]
127. Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling.
     J Biol Chem, 284(51): 35450-60. [Abstract] [Full-text]
128. Cancer research in rat models.
     Methods Mol Biol, 597: 445-58. [Abstract] [Full-text]
129. Application of microarray-based analysis of gene expression in the field of toxicogenomics.
     Methods Mol Biol, 597: 227-41. [Abstract] [Full-text]
130. Simultaneous analysis of expression of multiple redox-sensitive and apoptotic genes in hypothalamic neurons exposed to cholesterol secoaldehyde.
     Methods Mol Biol, 610: 263-84. [Abstract] [Full-text]
131. Determination of glutathione, mitochondrial transmembrane potential, and cytotoxicity in H9c2 cardiomyoblasts exposed to reactive oxygen and nitrogen species.
     Methods Mol Biol, 610: 51-61. [Abstract] [Full-text]
132. Evaluation of genotoxicity of Yanhuanglian dehydrocavidine (YHL-DC) in vitro and in vivo.
     Drug Chem Toxicol, 33(1): 103-10. [Abstract] [Full-text]
133. Renal expression of arachidonic acid metabolizing enzymes and RhoA/Rho kinases in fructose insulin resistant hypertensive rats.
     Mol Cell Biochem, 333(1): 203-9. [Abstract] [Full-text]
134. Nuclear xenobiotic receptor PXR-null mouse exhibits hypophosphatemia and represses the Na/Pi-cotransporter SLC34A2.
     Pharmacogenet Genomics, 20(1): 9-17. [Abstract] [Full-text]
135. Cadmium induces intracellular Ca2+- and H2O2-dependent apoptosis through JNK- and p53-mediated pathways in skin epidermal cell line.
     Toxicol Sci, 113(1): 127-37. [Abstract] [Full-text]
136. Aflatoxin B1 transfer and metabolism in human placenta.
     Toxicol Sci, 113(1): 216-25. [Abstract] [Full-text]
137. Arsenic (+ 3 oxidation state) methyltransferase and the methylation of arsenicals in the invertebrate chordate Ciona intestinalis.
     Toxicol Sci, 113(1): 70-6. [Abstract] [Full-text]
138. Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: toxic effects are determined by density of agglomerate structures, not fibrillar structures.
     Toxicol Sci, 113(1): 226-42. [Abstract] [Full-text]
139. In utero exposure to benzene disrupts fetal hematopoietic progenitor cell growth via reactive oxygen species.
     Toxicol Sci, 113(1): 207-15. [Abstract] [Full-text]
140. The effect of anti-eppin antibodies on ionophore A23187-induced calcium influx and acrosome reaction of human spermatozoa.
     Hum Reprod, 25(1): 29-36. [Abstract] [Full-text]
141. Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis.
     Toxicol Sci, 113(1): 27-36. [Abstract] [Full-text]
142. Partitioning of etofenprox under simulated California rice-growing conditions.
     Pest Manag Sci, 66(1): 28-34. [Abstract] [Full-text]
143. Ochratoxin A: is it present in breast milk samples obtained from mothers from Ankara, Turkey?
     J Appl Toxicol. [Abstract] [Full-text]
144. Atrial fibrillation after taser exposure in a previously healthy adolescent.
     Pediatr Emerg Care, 25(12): 851-3. [Abstract] [Full-text]
145. A Toll-Like Receptor 2/6 Agonist Reduces Allergic Airway Inflammation in Chronic Respiratory Sensitisation to Timothy Grass Pollen Antigens.
     Int Arch Allergy Immunol, 152(2): 131-139. [Abstract] [Full-text]
146. Sustained release methylphenidate for the treatment of ADHD in amphetamine abusers: A pilot study.
     Drug Alcohol Depend. [Abstract] [Full-text]
147. Stature Estimation from Foot Length Using Universal Regression Formula in a North Indian Population.
     J Forensic Sci. [Abstract] [Full-text]
148. Mechanisms of K(v)2.1 channel inhibition by celecoxib - modification of gating and channel block.
     Br J Pharmacol. [Abstract] [Full-text]
149. Workshop on Naturally Occurring Infections in Non-human Primates and Immunotoxicity Implications: Introduction.
     J Immunotoxicol. [Abstract] [Full-text]
150. Potentiation of the Human GABA(A) Receptor As a Novel Mode of Action of Lower-Chlorinated Non-Dioxin-Like PCBs (dagger).
     Environ Sci Technol. [Abstract] [Full-text]
151. Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: is there a connection?
     Proc Am Thorac Soc, 6(8): 638-47. [Abstract] [Full-text]
152. Localization of the lipopolysaccharide recognition complex in the human healthy and inflamed premature and adult gut.
     Inflamm Bowel Dis, 16(1): 68-75. [Abstract] [Full-text]
153. In vitro mammalian metabolism of the mitosis inhibitor zoxamide and the relationship to its in vitro toxicity.
     Xenobiotica, 40(1): 72-82. [Abstract] [Full-text]
154. Development of a personal bioaerosol sampler based on a conical cyclone with recirculating liquid film.
     J Occup Environ Hyg, 7(3): 156-62. [Abstract] [Full-text]
155. Forensic toxicology findings in deaths involving gamma-hydroxybutyrate.
     Int J Legal Med, 124(1): 1-6. [Abstract] [Full-text]
156. Post-translational regulation of cathepsin B, but not of other cysteine cathepsins, contributes to increased glioblastoma cell invasiveness in vitro.
     Pathol Oncol Res, 15(4): 711-23. [Abstract] [Full-text]
157. Drug uptake systems in liver and kidney: a historic perspective.
     Clin Pharmacol Ther, 87(1): 39-47. [Abstract] [Full-text]
158. A new ethyladenine antagonist of adenosine A(2A) receptors: Behavioral and biochemical characterization as an antiparkinsonian drug.
     Neuropharmacology. [Abstract] [Full-text]
159. Myocardial remodeling after infarction: the role of myofibroblasts.
     Nat Rev Cardiol, 7(1): 30-7. [Abstract] [Full-text]
160. A novel combination of Chinese medicines to treat advanced cancers and lymphomas in rats.
     Chin Med, 4: 22. [Abstract] [Full-text]
161. Cellular uptake and cytotoxic evaluation of fullerenol in different cell lines.
     Toxicology. [Abstract] [Full-text]
162. Exposure to manufactured nanoparticles in different workplaces.
     Toxicology. [Abstract] [Full-text]
163. Integrating WHO 2001-2008 criteria for the diagnosis of Myelodysplastic Syndrome (MDS): A case-case analysis of benzene exposure.
     Chem Biol Interact. [Abstract] [Full-text]
164. Vitellogenin (VTG) conservation in sea turtles: anti-VTG antibody in Chelonia mydas versus Caretta caretta.
     Physiol Biochem Zool, 83(1): 191-5. [Abstract] [Full-text]
165. The prostaglandin transporter OATP2A1 is expressed in human ocular tissues and transports the antiglaucoma prostanoid latanoprost.
     Invest Ophthalmol Vis Sci. [Abstract] [Full-text]
166. Commentary: Update on Animal Models for NTP Studies.
     Toxicol Pathol. [Abstract] [Full-text]
167. Chemical Carcinogenesis of the Gastrointestinal Tract in Rodents: An Overview with Emphasis on NTP Carcinogenesis Bioassays.
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174. Clinical pharmacology of methadone in dogs.
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175. Increased lung resistance after diesel particulate and ozone co-exposure not associated with enhanced lung inflammation in allergic mice.
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176. Lung inflammation is associated with reduced pulmonary nucleotide excision repair in vivo.
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177. d-Amino Acid Oxidase Generates Agonists of the Aryl Hydrocarbon Receptor from d-Tryptophan.
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178. Structural identification of Diindole agonists of the aryl hydrocarbon receptor derived from degradation of indole-3-pyruvic acid.
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179. Assessment of in vivo genotoxicity of the rodent carcinogen furan: evaluation of DNA damage and induction of micronuclei in mouse splenocytes.
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180. Further evaluation of a flow cytometric in vitro micronucleus assay in CHO-K1 cells: a reliable platform that detects micronuclei and discriminates apoptotic bodies.
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181. Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants.
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182. Inactivation of neuronal forebrain A receptors protects dopaminergic neurons in a mouse model of Parkinson's disease.
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183. Acetaminophen perturbed redox homeostasis in Wistar rat liver: protective role of aqueous Pterocarpus osun leaf extract.
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184. Factors to consider in the use of stem cells for pharmaceutic drug development and for chemical safety assessment.
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185. The activity of macrophage aggregates in the liver of flounder (Platichthys flesus) and wrasse (Symphodus melops) is associated with tissue damage.
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186. Health economics of blood transfusion safety - focus on sub-Saharan Africa.
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187. Uranium uptake and depuration in the aquatic invertebrate Chironomus tentans.
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189. Intermittent dosing of G-CSF to ameliorate carbon tetrachloride-induced liver fibrosis in mice.
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191. Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone.
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192. Topotecan triggers apoptosis in p53-deficient cells by forcing degradation of XIAP and survivin thereby activating caspase-3-mediated Bid cleavage.
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193. Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2.
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194. Inhibition of presynaptic release-facilitatory kainate autoreceptors by extracellular cyclic GMP.
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195. Noninvasive and invasive pulmonary function in mouse models of obstructive and restrictive respiratory diseases.
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196. Urine-based detection of intestinal tight junction loss.
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197. T3DB: a comprehensively annotated database of common toxins and their targets.
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198. Atorvastatin restores the impaired vascular endothelium-dependent relaxations mediated by nitric oxide and endothelium-derived hyperpolarizing factors but not hypotension in sepsis.
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199. Indoleamine 2,3-dioxygenase tissue distribution and cellular localization in mice: implications for its biological functions.
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200. Gut mucosal cell damage in meningococcal sepsis in children: relation with clinical outcome.
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201. Characterization of an AM404 analogue, N-(3-hydroxyphenyl)arachidonoylamide, as a substrate and inactivator of prostaglandin endoperoxide synthase.
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202. Design, evaluation and structure-Activity relationship studies of the AChE reactivators against organophosphorus pesticides.
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203. Ranitidine as an alcohol dehydrogenase inhibitor in acute methanol toxicity in rats.
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204. Analysis of endogenous glutathione-adducts and their metabolites.
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205. The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development.
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206. Disruption of the mGsta4 gene increases life span of C57BL mice.
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207. Differential expression of virulence and stress fitness genes between Escherichia coli O157:H7 strains with clinical or bovine-biased genotypes.
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208. On-line desorption of dried blood spots coupled to hydrophilic interaction/reversed-phase LC/MS/MS system for the simultaneous analysis of drugs and their polar metabolites.
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209. Preweaning manganese exposure causes hyperactivity, disinhibition, and spatial learning and memory deficits associated with altered dopamine receptor and transporter levels.
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210. Role of dopamine D(1) receptors in caffeine-mediated ERK phosphorylation in the rat brain.
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211. Exploring referral systems for injured patients in low-income countries: a case study from Cambodia.
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212. Differential Central NOS-NO Signaling Underlies Clonidine Exacerbation of Ethanol-Evoked Behavioral Impairment.
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213. Role of the bile salt export pump, BSEP, in acquired forms of cholestasis.
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214. In Silico Pharmacophore Model for Tabun-Inhibited Acetylcholinesterase Reactivators: A Study of Their Stereoelectronic Properties.
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215. Nutritional status and gastrointestinal microbes affect arsenic bioaccessibility from soils and mine tailings in the simulator of the human intestinal microbial ecosystem.
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216. Isomer-Specific Biotransformation Rates of a Perfluorooctane Sulfonate (PFOS)-Precursor by Cytochrome P450 Isozymes and Human Liver Microsomes.
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217. Yields of Glyoxal and Ring-Cleavage Co-Products from the OH Radical-Initiated Reactions of Naphthalene and Selected Alkylnaphthalenes.
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218. The organic selenium compound selenomethionine modulates bleomycin-induced DNA damage and repair in human leukocytes.
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219. The ubiquitin-proteasome system and nonsense-mediated mRNA decay in hypertrophic cardiomyopathy.
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220. Environmental-endocrine control of reproductive maturation in gastropods: implications for the mechanism of tributyltin-induced imposex in prosobranchs.
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221. Inter-laboratory control data for reproductive endpoints required in the OPPTS 870.3800/OECD 416 reproduction and fertility test.
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222. Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds.
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223. Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms.
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224. Fluoride-induced changes in haem biosynthesis pathway, neurological variables and tissue histopathology of rats.
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225. Congenital Syphilis: An Economic Evaluation of a Prevention Program in China.
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226. Liquid-air partition coefficients of 1,1-difluoroethane (HFC152a), 1,1,1-trifluoroethane (HFC143a), 1,1,1,2-tetrafluoroethane (HFC134a), 1,1,1,2,2-pentafluoroethane (HFC125) and 1,1,1,3,3-pentafluoropropane (HFC245fa).
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227. Polycyclic aromatic hydrocarbon metabolizing cytochrome P450s in freshly prepared uncultured rat blood lymphocytes.
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228. Eco-, geno- and human toxicology of bio-active nanoparticles for biomedical applications.
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229. Dorsomedial hypothalamus mediates autonomic, neuroendocrine, and locomotor responses evoked from the medial preoptic area.
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230. The GSTP1 Ile105 Val polymorphism modifies the metabolism of toluene di-isocyanate.
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231. Conducted Electrical Weapon Use by Law Enforcement: An Evaluation of Safety and Injury.
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232. Broad Spectrum in vitro Activity and in vivo Efficacy of the Antiviral Protein Griffithsin Against Emerging Viruses of the Family Coronaviridae.
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233. Blood lead levels association with 18-month all-cause mortality in patients with chronic peritoneal dialysis.
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234. Occurrence of anthropogenic and naturally-produced organohalogenated compounds in tissues of Black Sea harbour porpoises.
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235. An examination of serotonin and psychological variables in the relationship between exercise and mental health.
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236. Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazoline.
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237. Mode of Action Considerations in the Quantitative Assessment of Tumour Responses in the Liver.
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238. Increased Hepatic and Decreased Urinary Metallothionein in Rats after Cessation of Oral Cadmium Exposure.
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239. Juvenile animal toxicity study designs to support pediatric drug development.
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240. Developmental and reproductive toxicology studies in nonhuman primates.
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241. Direct and transgenerational impact on Daphnia magna of chemicals with a known effect on DNA methylation.
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242. Development of a high-throughput screening for nerve agent detoxifying materials using a fully-automated robot-assisted biological assay.
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243. Laminin {alpha}4-Null Mutant Mice Develop Chronic Kidney Disease with Persistent Overexpression of Platelet-Derived Growth Factor.
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244. The HIV-1 Viral Protein Tat Increases Glutamate and Decreases GABA Exocytosis from Human and Mouse Neocortical Nerve Endings.
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245. Smoking in prison: a hierarchical approach at the crossroad of personality and childhood events.
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246. A disintegrin and metalloproteinase 17 (ADAM17) mediates inflammation-induced shedding of syndecan-1 and -4 by lung epithelial cells.
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247. No association between variant DNA repair genes and prostate cancer risk among men of African descent.
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248. Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy.
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249. Nigerian Bonny Light Crude Oil Disrupts Antioxidant Systems in Testes and Sperm of Rats.
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250. Aging reveals a role for nigral tyrosine hydroxylase ser31 phosphorylation in locomotor activity generation.
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251. Liquid chromatography-tandem mass spectrometry for the determination of paclitaxel in rat plasma after intravenous administration of poly(l-glutamic acid)-alanine-paclitaxel conjugate.
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252. Cooperation of NAD(P)H:quinone oxidoreductase 1 and UDP-glucuronosyltransferases reduces menadione cytotoxicity in HEK293 cells.
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253. Generation of functional human hepatic endoderm from human induced pluripotent stem cells.
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254. Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 3'-(Substituted Phenyl)epibatidine Analogues. Nicotinic Partial Agonists ( perpendicular).
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255. Mechanisms for increased expression of cholesterol 7alpha-hydroxylase (Cyp7a1) in lactating rats.
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256. Antioxidant and antimutagenic effect of quercetin against DEN induced hepatotoxicity in rat.
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257. Analgesic and antiinflammatory activity of Morinda citrifolia L. (Noni) fruit.
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258. Screening of some Kenyan medicinal plants for antibacterial activity.
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259. Insulin glargine safety in pregnancy: a transplacental transfer study.
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260. Phynx: an open source software solution supporting data management and web-based patient-level data review for drug safety studies in the general practice research database and other health care databases.
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261. In vitro cell-toxicity screening as an alternative animal model for coral toxicology: effects of heat stress, sulfide, rotenone, cyanide, and cuprous oxide on cell viability and mitochondrial function.
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262. Concentration Response Functions for Ultrafine Particles and All-Cause Mortality and Hospital Admissions: Results of a European Expert Panel Elicitation.
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263. A hospital-based case control study of aplastic anemia in Shanghai, China.
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264. Tissue factor-deficiency and protease activated receptor-1-deficiency reduce inflammation elicited by diet-induced steatohepatitis in mice.
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265. Black tea reduces uric acid and C-reactive protein levels in humans susceptible to cardiovascular diseases.
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266. Predicting the hepatocarcinogenic potential of alkenylbenzene flavoring agents using toxicogenomics and machine learning.
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267. Effects of nutrition relevant mixtures of phytoestrogens on steroidogenesis, aromatase, estrogen, and androgen activity.
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268. Limited Sampling Strategies for Therapeutic Drug Monitoring of Linezolid in Patients With Multidrug-Resistant Tuberculosis.
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269. Retinoic acid activation of peroxisome proliferation-activated receptor delta represses obesity and insulin resistance.
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270. Evaluation of the polyphenol composition and antioxidant activity of African variety of Dacryodes edulis (G.Don) H.J Lam fruit.
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271. Polyphenol composition and antioxidant potential of Hibiscus esculentus L. fruit cultivated in Nigeria.
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272. Carica papaya (Paw-Paw) unripe fruit may be beneficial in ulcer.
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